Exploring Ibogaine’s Potential as a Cancer Therapy: Targeting Sigma Receptors

Exploring Ibogaine’s Potential as a Cancer Therapy: Targeting Sigma Receptors By Troy Valencia Blog Recap Sigma receptors, particularly sigma-2 (σ2), are emerging as key targets in cancer therapy due to their overexpression in proliferating tumor cells and involvement in critical cellular processes such as endoplasmic reticulum (ER) stress, calcium signaling, and apoptosis. Ibogaine, a psychoactive […]
Ibogaine: a promising alternative for treating generalized anxiety disorder through neurotransmitter modulation

Ibogaine: A promising alternative for treating generalized anxiety disorder through neurotransmitter modulation By Troy Valencia Generalized Anxiety Disorder (GAD) is a chronic condition characterized by pervasive and excessive worry that disrupts daily functioning and significantly impairs quality of life (American Psychiatric Association, 2022). Traditional treatment approaches include cognitive-behavioral therapy (CBT) and pharmacological interventions such as […]
Exploring Iboga And Ibogaine: Ancient Healing With A Modern Approach

Exploring Iboga and Ibogaine: Ancient Healing with a Modern Approach By Troy Valencia At Root and Wisdom, we deeply respect Iboga for its roots in traditional healing and its transformative potential in today’s mental health landscape. This sacred plant from Central Africa has long been used in spiritual ceremonies, but in recent decades, ibogaine—an alkaloid […]
Research Paper: Iboga and Neuroplasticity: A Path to Stroke Recovery
Research paper: Iboga and neuroplasticity: a path to Stroke Recovery By Troy Valencia Neuroplasticity—the brain’s ability to reorganize itself by forming new neural connections—is a cornerstone of our evolving understanding of brain and behavior. This ability is essential for recovery from various neurological injuries, including stroke. With the brain’s capacity for rewiring in response to […]
The Benefits of Microdosing Iboga – A Holistic Approach to Healing and Cognitive Enhancement

The Benefits of Microdosing Iboga – A Holistic Approach to Healing and Cognitive Enhancement By Troy Valencia Iboga, a powerful psychoactive alkaloid found in the root bark of the Tabernanthe iboga plant, has traditionally been used in Central and West African spiritual ceremonies. In recent years, Iboga has gained recognition for its potential benefits in […]
Iboga and circadian rhythm resetting: a path to restoring balance
Iboga and circadian rhythm resetting: a path to restoring balance By Troy Valencia At Root and Wisdom, we understand that modern life often throws our internal rhythms out of balance. Whether it is the toll of shift work, jet lag, or long-term sleep disturbances, disruptions to our circadian rhythms—our body’s internal biological clock—can significantly impact […]
Dreams and Plant Medicine: A psychospiritual Exploration

Dreams and Plant Medicine: A psychospiritual Exploration By Troy Valencia At Root and Wisdom, we honor Iboga, a sacred African plant known for its powerful ability to open the door to the unconscious, much like the realm of dreams. Through Jungian dreamwork, we understand that the unconscious communicates in symbols and metaphors, offering us deep […]
Flowing with The Natural World Through Iboga

Flowing with the natural world through iboga By Troy Valencia One of the most valuable insights I’ve gained from working with ibgoa is the awareness to observe the seasonal flow in my life, just as I do the seasonal flow of nature. This rhythmic pulse of the natural world influences us on physical and emotional levels, […]
